You are here

Share:

Product Type

Development Stage

Therapeutic Area

Institutes and Centers

Search Technologies

Showing 1-4 of 4 results found

Monoclonal Antibody Fragments for Targeting Therapeutics to Growth Plate Cartilage

In collaboration with the National Cancer Institute (NCI), researchers at The Eunice Kennedy Shriver National Institute on Child Health and Human Development (NICHD) have discovered monoclonal antibodies that bind to matrilin-3, a protein specifically expressed in cartilage tissue, that could be used for treating or inhibiting growth plate disorders, such as a skeletal dysplasia or short stature. The monoclonal antibodies can also be used to target therapeutic agents, such as those for anti-arthritis, to cartilage tissue. NICHD seeks statements of capability or interest from parties interested in collaborative research to co-develop, evaluate, and/or commercialize treatment of skeletal disorders using targeting antibodies.
  • Therapeutics

Composite Gels and Methods of their Use in Tissue Repair, Drug Delivery, and as Implants

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks research and development partners or licensees for novel composite hydrogels that can be used in tissue repair and other applications. Single gel networks used in tissue engineering and tissue repair applications generally become softer and more flaccid as they swell. The gels described in this technology, however, which comprise a swellable crosslinked polymer hydrogel dispersed in a crosslinked polymer matrix, mimic critical material properties of tissue extracellular matrix (ECM), for instance, becoming stiffer and tougher upon swelling.
  • Devices

Tamperless Tensor Elastography Imaging

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks research co-development partners and/or licensees for the development of tamperless tensor elastography imaging in assessing disease (e.g., cancer), normal and abnormal developmental processes, degeneration and trauma in the brain and other soft tissues, and other applications.
  • Diagnostics

La Protein as a Novel Regulator of Osteoclastogenesis

The National Institute of Child Health and Human Development (NICHD) seeks research co-development partners and/or licensees for the further development of methods to target the La protein for the regulation of osteoclastogenesis.
  • Therapeutics