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Showing 21-40 of 52 results found

Robotic Exoskeleton for Treatment of Crouch Gait in Children with Cerebral Palsy (CP)

Researchers at the National Institutes of Health Clinical Center (NIHCC) and Northern Arizona University (NAU) seek licensing and/or co-development research collaborations for a wearable, pediatric, robotic exoskeleton that facilitates knee extension during walking to provide motorized movement assistance and training through the gait cycle. The Robotic Exoskeleton is specifically designed for therapy of crouch gait in children with cerebral palsy (CP). The design is a customizable human-machine interface that allows an individualized assistance protocol to help preserve and enhance muscle strength and control. Early clinical results from this intervention appear promising for a condition having few effective long-term interventions.
  • Devices

Mitotic Figures Electronic Counting Application for Surgical Pathology

National Cancer Institute (NCI) researchers have developed a novel software tool for uniform recording of Mitotic Figure (MF) counts via conventional and/or digital microscopy. With this technology, diagnostic centers can standardize electronic recording, summation, and transcription of clinical data during surgical pathology examination. NCI seeks licensing partners to further develop this application for use in diagnosis and detection of malignant cancers.
  • Software

Biomarker Analysis Software for High-Throughput Diagnostic Multiplex Data

Extracellular vesicles (EVs) are lipid spheres released from cells. EVs contain proteins that can serve as diagnostic biomarkers indicating the cell state at time of release. Improved detection and phenotyping of EVs and their protein cargo could lead to better cancer diagnostic and prognostic tests, as well as improved therapeutic uses. The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a software package that performs high-throughput multi-dimensional analysis of EV biomarkers.
  • Software

Progressive and Multipath Neural Network for Medical Image Segmentation

Researchers at the National Institutes of Health Clinical Center (NIHCC) developed a technology that improves segmentation detail levels for anatomical structures in medical images through a new, deep learning approach. Difficult anatomical features, often segmented incorrectly with other image segmentation methods, are correctly segmented and identified using this novel technology, which is available for licensing or co-development.
  • Software

Zirconium-89 PET Imaging Agent for Cancer

This technology is a new generation of rationally designed chelating agents that improve the complexation of Zirconium-89 for PET imaging of cancers.
  • Diagnostics
  • Research Tools

Bacteriophage Based-Vaccine System

Scientists at the National Cancer Institute (NCI) developed an engineered bacteriophage lambda () vector for displaying antigens to be used as a vaccine in treatment of cancers and infectious diseases. The NCI seeks licensing and/or co-development research collaborations for further development of the Bacteriophage based-vaccine system.
  • Vaccines

Clinical Imaging with Acoustic Wave or Photoacoustic Tomosynthesis

Ultrasound-based cancer screening and biopsy imaging technique are a critical clinical need. Ultrasound based biopsy imaging can provide a real-time modality for lower cost that is comparable to, or complimentary to MRI imaging. Researchers at the NIH Clinical Center seek licensing and/or co-development research collaborations for Tissue Characterization with Acoustic Wave Tomosynthesis.
  • Diagnostics

Software for Automated Generation of Density Maps

Available for licensing is computer software for the automated generation of density maps of macromolecular structures from a series of 2D digital micrographs of frozen hydrated specimens collected using an electron microscope equipped with an ultra-cooled computerized stage.
  • Software

RNASEH-Assisted Detection Assay for RNA

The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for the development and commercialization of a diagnostic assay that detects sequence-specific (viral) RNA.
  • Diagnostics

Polymer-Cast Inserts for Cell Histology and Microscopy

The National Cancer Institute (NCI) seeks co-development partners and/or licensees for polymer-cast inserts for cell histology and microscopy; a system for high throughput three-dimensional (3D) cell culture and screening microscopy.
  • Research Tools

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