The National Cancer Institute (NCI) seeks research co-development or licensees for a precision medicine approach that classifies patients’ DLBCL into genetic subtypes that are predictive of treatment response.
The National Cancer Institute (NCI) seeks licensees for an automated digital pathology device which integrates tissue sectioning, staining, and image acquisition. The device is compatible with high-throughput data analyses.
The National Cancer Institute (NCI) seeks co-development partners and/or licensees for polymer-cast inserts for cell histology and microscopy; a system for high throughput three-dimensional (3D) cell culture and screening microscopy.
Scientists at the National Eye Institute (NEI) have developed an embryo culture chamber, which can be used to culture and image embryos. The chamber allows for the continuous imaging of the embryo for the culture period. NEI seeks research collaborations and/or licensees for the development of this culture and imaging chamber for murine embryos.
The National Cancer Institute (NCI) seeks licensees for humanized mice that express the human isomer of mesothelin (MSLN) in the thyroid. NCI created Bl6/TPO mice for studies of mesothelin as a target for research, diagnostic, or therapeutics involving human cancers.
Scientists at The National Cancer Institute (NCI) and The National Institute of Neurological Disorders and Stroke (NINDS) have invented a method of imaging glucose metabolism in vivo using MRI chemical shift imaging (CSI) experiments that relies on a simple, but robust and efficient, post-processing procedure by the higher dimensional analog of singular value decomposition, tensor decomposition. This new technology is denoising software for MRIs that significantly improves the measurement of low-intensity signals without the need for dynamic nuclear polarization (DNP). The scientists seek research co-development partners and/or licensees for their invention.
The National Cancer Institute (NCI) seeks research, co-development, or licensing partners for software that uses computational approaches in cancer diagnosis. NCI researchers have recently developed a computational approach for detecting, quantifying, and mapping Mitotic Hotspots in whole slide images of tumor tissue. This technology has demonstrated high reproducibility that is unaffected by diagnostic skill or fatigue, allowing standardization of tumor cell proliferation assessment across institutions.
National Cancer Institute (NCI) researchers have developed a novel software tool for uniform recording of Mitotic Figure (MF) counts via conventional and/or digital microscopy. With this technology, diagnostic centers can standardize electronic recording, summation, and transcription of clinical data during surgical pathology examination. NCI seeks licensing partners to further develop this application for use in diagnosis and detection of malignant cancers.
Researchers at the National Cancer Institute (NCI) seek licensing for an improved cell line called Tni-FNL which is capable of high level expression of heterologous proteins using baculovirus expression systems.
This invention pertains to a system for continuous observation of rodents in home-cage environments with the specific aim to facilitate the quantification of activity levels and behavioral patterns for mice housed in a commercial ventilated cage rack. The National Cancer Institute’s Radiation Biology Branch seeks partners interested in collaborative research to co-develop a video monitoring system for laboratory animals.
The NCI seeks licensees or co-development partners for this technology, which describes compositions, methods and kits for identifying, characterizing biomolecules expressed in a sample that are associated with the presence, the development, or progression of cancer.
Researchers at the National Institutes of Health Clinical Center (NIHCC) and Northern Arizona University (NAU) seek licensing and/or co-development research collaborations for a wearable, pediatric, robotic exoskeleton that facilitates knee extension during walking to provide motorized movement assistance and training through the gait cycle. The Robotic Exoskeleton is specifically designed for therapy of crouch gait in children with cerebral palsy (CP). The design is a customizable human-machine interface that allows an individualized assistance protocol to help preserve and enhance muscle strength and control. Early clinical results from this intervention appear promising for a condition having few effective long-term interventions.
The NCI Radiation Oncology Branch and the NHLBI Laboratory of Single Molecule Biophysics seek parties to co-develop fluorescent nanodiamonds for use as in vivo and in vitro optical tracking probes toward commercialization.
Device is used to guide a stream of oxygen or carbon dioxide over a dish of cells during fluorescence microscopy. Invention includes the 3D printing software to create the device. The device makes it possible to easily provide a steady source of oxygen or carbon dioxide to cells while operating a fluorescent microscope to oxidize fluorophores for later visualization in electron microscopy. NCI seeks commercial partners to license this technology.