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Use of a Modified Adaptor Molecule LAT to Improve Immunotherapy for Cancer and Other Diseases

Researchers at the NCI have developed a method of improving the immune response in cancer immunotherapy by exploiting in the role of the Linker Adapted for T-Cell Signaling (LAT) molecule. The LAT molecular can enhance signaling through TCRs, thus, improving a patient’s own immune response to cancer or infectious diseases.

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Use of a Modified Adaptor Molecule LAT to Improve Immunotherapy for Cancer and Other Diseases