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Device to guide oxygen over cells for photo-oxidation

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Summary
Device is used to guide a stream of oxygen or carbon dioxide over a dish of cells during fluorescence microscopy. Invention includes the 3D printing software to create the device. The device makes it possible to easily provide a steady source of oxygen or carbon dioxide to cells while operating a fluorescent microscope to oxidize fluorophores for later visualization in electron microscopy. NCI seeks commercial partners to license this technology.
NIH Reference Number
E-244-2016
Product Type
  • Research Tools
Keywords
  • Transmission Electron Microscopy, TEM
Collaboration Opportunity
This invention is available for licensing.
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Description of Technology

Researchers at the NCI Laboratory for Cell Biology have invented a device to guide a stream of oxygen or carbon dioxide over a dish of cells during fluorescence microscopy. The invention includes the 3D printing software to create the device.  The device facilitates application of a steady source of oxygen or carbon dioxide to cells while operating a fluorescent microscope to oxidize fluorophores for subsequent visualization via electron microscopy. 

Potential Commercial Applications
  • Device facilitates use of Transmission Electron Microscopy (TEM) in cancer research
Inventor(s)

Giovanna Grandinetti (NCI)

Development Stage
  • Prototype
Patent Status
  • Research Material: NIH will not pursue patent prosecution for this technology
Related Technologies
Therapeutic Area
  • Cancer/Neoplasm
Updated
Wednesday, March 21, 2018